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Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1

The unregulated activation of STAT3 has been demonstrated to occur in many cancers and enhances tumour growth, migration, and invasion. Stimulation by cytokines, growth factors, and hormones triggers this activation by phosphorylating STAT3 at tyrosine 705. Novel imidazopyridine compounds were synth...

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Detalles Bibliográficos
Autores principales:	Su, Jung-Chen, Chang, Chuan-Hsun, Wu, Szu-Hsien, Shiau, Chung-Wai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161598/ https://www.ncbi.nlm.nih.gov/pubmed/30261753 http://dx.doi.org/10.1080/14756366.2018.1497019

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