Metformin and its sulphonamide derivative simultaneously potentiateanti-cholinesterase activity of donepezil and inhibit beta-amyloid aggregation

The aim of this study was to assess in vitro the effects of sulphenamide and sulphonamide derivatives of metformin on the activity of human acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), establish the type of inhibition, and assess the potential synergism between biguanides and donep...

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Detalles Bibliográficos
Autores principales: Markowicz-Piasecka, Magdalena, Huttunen, Kristiina M., Sikora, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161601/
https://www.ncbi.nlm.nih.gov/pubmed/30251898
http://dx.doi.org/10.1080/14756366.2018.1499627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161601/
https://www.ncbi.nlm.nih.gov/pubmed/30251898
http://dx.doi.org/10.1080/14756366.2018.1499627

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