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Enhanced gene transfection efficiency by low-dose 25 kDa polyethylenimine by the assistance of 1.8 kDa polyethylenimine

Gene therapy is a promising strategy for treatments of various diseases. Efficient and safe introduction of therapeutic genes into targeted cells is essential to realize functions of the genes. High-molecular-weight polyethylenimines (HMW PEIs) including 25 kDa branched PEI and 22 kDa linear PEI are...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Chen, Zhiyi, Du, Meng, Li, Yue, Chen, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161618/
https://www.ncbi.nlm.nih.gov/pubmed/30241446
http://dx.doi.org/10.1080/10717544.2018.1510065