Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks

The concentrations of insulin selectively regulate multiple cellular functions. To understand how insulin concentrations are interpreted by cells, we constructed a trans-omic network of insulin action in FAO hepatoma cells using transcriptomic data, western blotting analysis of signaling proteins, a...

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Detalles Bibliográficos
Autores principales: Kawata, Kentaro, Hatano, Atsushi, Yugi, Katsuyuki, Kubota, Hiroyuki, Sano, Takanori, Fujii, Masashi, Tomizawa, Yoko, Kokaji, Toshiya, Tanaka, Kaori Y., Uda, Shinsuke, Suzuki, Yutaka, Matsumoto, Masaki, Nakayama, Keiichi I., Saitoh, Kaori, Kato, Keiko, Ueno, Ayano, Ohishi, Maki, Hirayama, Akiyoshi, Soga, Tomoyoshi, Kuroda, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161632/
https://www.ncbi.nlm.nih.gov/pubmed/30267682
http://dx.doi.org/10.1016/j.isci.2018.07.022

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