Modeling and antitumor studies of a modified L–penetratin peptide targeting E2F in lung cancer and prostate cancer

E2F1-3a overexpression due to amplification or to mutation or loss of the retinoblastoma gene, induces genes involved in DNA synthesis and leads to abnormal cellular proliferation, tumor growth, and invasion. Therefore, inhibiting the overexpression of one or more of these activating E2Fs is a recog...

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Detalles Bibliográficos
Autores principales: Shaik, Tazeem, Rather, Gulam M., Bansal, Nitu, Minko, Tamara, Garbuzenko, Olga, Szekely, Zoltan, Abali, Emine E., Banerjee, Debabrata, Kerrigan, John E., Scotto, Kathleen W., Bertino, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161789/
https://www.ncbi.nlm.nih.gov/pubmed/30279956
http://dx.doi.org/10.18632/oncotarget.26064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161789/
https://www.ncbi.nlm.nih.gov/pubmed/30279956
http://dx.doi.org/10.18632/oncotarget.26064

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