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Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress
Oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). The dry form of AMD (geographic atrophy) is characterized by loss of RPE, photoreceptors, and macular pigments. The cumulative effects of oxidative stress impact mitochondrial function in RPE. In Sod2(flox/...
Autores principales: | Biswal, Manas R., Justis, Bradley D., Han, Pingyang, Li, Hong, Gierhart, Dennis, Dorey, Cheryl K., Lewin, Alfred S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161850/ https://www.ncbi.nlm.nih.gov/pubmed/30265681 http://dx.doi.org/10.1371/journal.pone.0203816 |
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