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Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). The dry form of AMD (geographic atrophy) is characterized by loss of RPE, photoreceptors, and macular pigments. The cumulative effects of oxidative stress impact mitochondrial function in RPE. In Sod2(flox/...

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Detalles Bibliográficos
Autores principales:	Biswal, Manas R., Justis, Bradley D., Han, Pingyang, Li, Hong, Gierhart, Dennis, Dorey, Cheryl K., Lewin, Alfred S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161850/ https://www.ncbi.nlm.nih.gov/pubmed/30265681 http://dx.doi.org/10.1371/journal.pone.0203816

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