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The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro
It has been proposed that pancreatic beta-cell dysfunction in type 2 diabetes is promoted by oxidative stress caused by NADPH oxidase (Nox) over-activity. The aim of the present study was to evaluate the efficacy of novel Nox inhibitors as protective agents against cytokine- or high glucose + palmit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161897/ https://www.ncbi.nlm.nih.gov/pubmed/30265686 http://dx.doi.org/10.1371/journal.pone.0204271 |