Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming

While Notch signaling has been proposed to play a key role in fibrosis, the direct molecular pathways targeted by Notch signaling and the precise ligand and receptor pair that are responsible for kidney disease remain poorly defined. In this study, we found that JAG1 and NOTCH2 showed the strongest...

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Detalles Bibliográficos
Autores principales: Huang, Shizheng, Park, Jihwan, Qiu, Chengxiang, Chung, Ki Wung, Li, Szu-yuan, Sirin, Yasemin, Han, Seung Hyeok, Taylor, Verdon, Zimber-Strobl, Ursula, Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161902/
https://www.ncbi.nlm.nih.gov/pubmed/30226866
http://dx.doi.org/10.1371/journal.pbio.2005233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161902/
https://www.ncbi.nlm.nih.gov/pubmed/30226866
http://dx.doi.org/10.1371/journal.pbio.2005233

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