Cargando…
Emerging challenges in understanding trypanosome antigenic variation
Many pathogens evade host immunity by periodically changing the proteins they express on their surface — a phenomenon termed antigenic variation. An extreme form of antigenic variation, based around switching the composition of a variant surface glycoprotein (VSG) coat, is exhibited by the African t...
Autores principales: | McCulloch, Richard, Cobbold, Christina A., Figueiredo, Luisa, Jackson, Andrew, Morrison, Liam J., Mugnier, Monica R., Papavasiliou, Nina, Schnaufer, Achim, Matthews, Keith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162063/ https://www.ncbi.nlm.nih.gov/pubmed/30271884 http://dx.doi.org/10.1042/ETLS20170104 |
Ejemplares similares
-
The within-host dynamics of African trypanosome infections
por: Matthews, Keith R., et al.
Publicado: (2015) -
Molecular mechanisms underlying the control of antigenic variation in African trypanosomes
por: Horn, David, et al.
Publicado: (2010) -
Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei
por: Mugnier, Monica R., et al.
Publicado: (2016) -
Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation
por: Pinger, Jason, et al.
Publicado: (2017) -
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control
por: Glover, Lucy, et al.
Publicado: (2013)