Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature

Hidradenitis suppurativa (HS) is a chronic skin disease of the pilo-sebaceous apocrine unit characterized by significant inflammation and an impaired quality of life. The pathogenesis of HS remains unclear. To determine the HS skin and blood transcriptomes and HS blood proteome, patient data from pr...

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Detalles Bibliográficos
Autores principales: Hoffman, Lauren K., Tomalin, Lewis E., Schultz, Gregory, Howell, Michael D., Anandasabapathy, Niroshana, Alavi, Afsaneh, Suárez-Fariñas, Mayte, Lowes, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162087/
https://www.ncbi.nlm.nih.gov/pubmed/30265680
http://dx.doi.org/10.1371/journal.pone.0203672

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