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Inflammation independent TL1A-mediated Intestinal Fibrosis is Dependent on the Gut Microbiome

Tumor necrosis factor-like cytokine 1A (TL1A, TNFSF15) is implicated in inflammatory bowel disease (IBD), modulating the location and severity of intestinal inflammation and fibrosis. TL1A expression is increased in inflamed gut mucosa and associated with fibrostenosing Crohn’s disease. Tl1a-overexp...

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Detalles Bibliográficos
Autores principales:	Jacob, Noam, Jacobs, Jonathan P., Kumagai, Kotaro, Ha, Connie W.Y., Kanazawa, Yoshitake, Lagishetty, Venu, Altmayer, Katherine, Hamill, Ariel M., Von Arx, Aimee, Sartor, R. Balfour, Devkota, Suzanne, Braun, Jonathan, Michelsen, Kathrin S., Targan, Stephan R, Shih, David Q
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162160/ https://www.ncbi.nlm.nih.gov/pubmed/29988118 http://dx.doi.org/10.1038/s41385-018-0055-y

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