USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

We have previously demonstrated that USP24 is involved in cancer progression. Here, we found that USP24 expression is upregulated in M2 macrophages and lung cancer cells. Conditioned medium from USP24-knockdown M2 macrophages decreases the migratory and chemotactic activity of lung cancer cells and...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Chang, Wu, Yu-Syuan, Hung, Chia-Yang, Wang, Shao-An, Young, Ming-Jer, Hsu, Tsung-I, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162259/
https://www.ncbi.nlm.nih.gov/pubmed/30266897
http://dx.doi.org/10.1038/s41467-018-06178-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162259/
https://www.ncbi.nlm.nih.gov/pubmed/30266897
http://dx.doi.org/10.1038/s41467-018-06178-1

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