Cargando…

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

We have previously demonstrated that USP24 is involved in cancer progression. Here, we found that USP24 expression is upregulated in M2 macrophages and lung cancer cells. Conditioned medium from USP24-knockdown M2 macrophages decreases the migratory and chemotactic activity of lung cancer cells and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yi-Chang, Wu, Yu-Syuan, Hung, Chia-Yang, Wang, Shao-An, Young, Ming-Jer, Hsu, Tsung-I, Hung, Jan-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162259/ https://www.ncbi.nlm.nih.gov/pubmed/30266897 http://dx.doi.org/10.1038/s41467-018-06178-1

Ejemplares similares

Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction
por: Jaffry, Uzma, et al.
Publicado: (2023)

USP7 counteracts SCF(βTrCP)- but not APC(Cdh1)-mediated proteolysis of Claspin
por: Faustrup, Helene, et al.
Publicado: (2009)

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
por: Bufalieri, Francesca, et al.
Publicado: (2019)

β-TrCP1 facilitates cell cycle checkpoint activation, DNA repair, and cell survival through ablation of β-TrCP2 in response to genotoxic stress
por: Islam, Sehbanul, et al.
Publicado: (2021)

NORE1A Regulates MDM2 Via β-TrCP
por: Schmidt, M. Lee, et al.
Publicado: (2016)

Structural basis of βTrCP1-associated GLI3 processing
por: Shafique, Shagufta, et al.
Publicado: (2019)

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy
por: Herrero-Ruiz, Joaquín, et al.
Publicado: (2014)

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression
por: Seki, Akiko, et al.
Publicado: (2008)

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation
por: Zhang, Rui, et al.
Publicado: (2017)

β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
por: Wang, Dongping, et al.
Publicado: (2019)

β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
por: Cheng, Yun, et al.
Publicado: (2016)

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase
por: Magliozzi, Roberto, et al.
Publicado: (2015)

Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis
por: Krishnamurthy, Pranathi Meda, et al.
Publicado: (2017)

The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
por: Cui, Danrui, et al.
Publicado: (2019)

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor
por: Paul, Debasish, et al.
Publicado: (2022)

SCF(βTrCP)-mediated degradation of SHARP1 in triple-negative breast cancer
por: Enriqué Steinberg, Juliana Haydeé, et al.
Publicado: (2023)

USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy
por: Wang, Shao-An, et al.
Publicado: (2020)

PLK1 and β-TrCP-Dependent Ubiquitination and Degradation of Rap1GAP Controls Cell Proliferation
por: Wang, Dejie, et al.
Publicado: (2014)

TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
por: Ma, Ying, et al.
Publicado: (2018)

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP
por: Tatarskiy, Victor V., et al.
Publicado: (2017)

Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer
por: Tseng, Ruo-Chia, et al.
Publicado: (2015)

Correction: TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor
por: Gluschnaider, Udi, et al.
Publicado: (2010)

Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase
por: Jiang, Hui, et al.
Publicado: (2011)

Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
por: Benary, Uwe, et al.
Publicado: (2019)

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
por: Mavrommati, Ioanna, et al.
Publicado: (2018)

F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2
por: Lee, Cheol-Jung, et al.
Publicado: (2021)

USP24 promotes drug resistance during cancer therapy
por: Wang, Shao-An, et al.
Publicado: (2021)

CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway
por: Bu, Xin, et al.
Publicado: (2021)

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release
por: Tervo, Hanna-Mari, et al.
Publicado: (2011)

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
por: Chan, Eunice H. Y., et al.
Publicado: (2008)

Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
por: Maluquer de Motes, Carlos, et al.
Publicado: (2017)

Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis
por: Xiong, Xiufang, et al.
Publicado: (2018)

MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells
por: Xu, Huanji, et al.
Publicado: (2019)

The novel β-TrCP protein isoform hidden in circular RNA confers trastuzumab resistance in HER2-positive breast cancer
por: Wang, Shengting, et al.
Publicado: (2023)

Inter-Fighting between Influenza A Virus NS1 and β-TrCP: A Novel Mechanism of Anti-Influenza Virus
por: Sun, Haiwei, et al.
Publicado: (2022)

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking
por: Mitchell, Richard S., et al.
Publicado: (2009)

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1
por: Blees, Johanna S., et al.
Publicado: (2012)

GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression
por: Zhu, Yuekun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_klb17bep4afjpg7ino4taae9lp