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An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction. The free energy difference of cyclic-nucleotide (cAMP/cGMP) binding/unbinding is translated into mechanical work to modulate the open/closed probability of the pore, i.e., gating. Despite the rec...

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Detalles Bibliográficos
Autores principales:	Marchesi, Arin, Gao, Xiaolong, Adaixo, Ricardo, Rheinberger, Jan, Stahlberg, Henning, Nimigean, Crina, Scheuring, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162275/ https://www.ncbi.nlm.nih.gov/pubmed/30266906 http://dx.doi.org/10.1038/s41467-018-06414-8

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