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Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge

Our laboratory reported that facial skin blood flow may serve as a sensitive tool to assess an emotional status and that both prefrontal oxygenation (as index of regional cerebral blood flow) and facial skin blood flow decrease during positively-charged emotional stimulation, without changing hand s...

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Autores principales: Matsukawa, Kanji, Asahara, Ryota, Yoshikawa, Miho, Endo, Kana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162331/
https://www.ncbi.nlm.nih.gov/pubmed/30266925
http://dx.doi.org/10.1038/s41598-018-32752-0
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author Matsukawa, Kanji
Asahara, Ryota
Yoshikawa, Miho
Endo, Kana
author_facet Matsukawa, Kanji
Asahara, Ryota
Yoshikawa, Miho
Endo, Kana
author_sort Matsukawa, Kanji
collection PubMed
description Our laboratory reported that facial skin blood flow may serve as a sensitive tool to assess an emotional status and that both prefrontal oxygenation (as index of regional cerebral blood flow) and facial skin blood flow decrease during positively-charged emotional stimulation, without changing hand skin blood flow and arterial pressure. However, the focal location of the prefrontal responses in concentration of oxygenated haemoglobin (Oxy-Hb) that correlate with peripheral autonomic reaction remained unknown. This study was undertaken using 22-channel near-infrared spectroscopy to reveal spatial distribution of the responses in Oxy-Hb within the prefrontal cortex (PFC) during emotionally-charged audiovisual stimulation. Pleasantly-charged (comedy) stimulation caused a substantial decrease of Oxy-Hb in all regions of the PFC in 18 subjects, especially in the rostroventral frontopolar PFC, whereas negatively-charged (horror) or neutral stimulation (landscape) exhibited a weaker decrease or insignificant change in the prefrontal Oxy-Hb. In the rostral parts of the dorsolateral and ventral frontopolar PFC, the oxygenation response during comedy stimulation exhibited the most significant positive correlation with the decrease in facial skin blood flow. Thus the rostral regions of the PFC play a role in recognition and regulation of positive emotion and may be linked with neurally-mediated vasoconstriction of facial skin blood vessels.
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spelling pubmed-61623312018-10-02 Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge Matsukawa, Kanji Asahara, Ryota Yoshikawa, Miho Endo, Kana Sci Rep Article Our laboratory reported that facial skin blood flow may serve as a sensitive tool to assess an emotional status and that both prefrontal oxygenation (as index of regional cerebral blood flow) and facial skin blood flow decrease during positively-charged emotional stimulation, without changing hand skin blood flow and arterial pressure. However, the focal location of the prefrontal responses in concentration of oxygenated haemoglobin (Oxy-Hb) that correlate with peripheral autonomic reaction remained unknown. This study was undertaken using 22-channel near-infrared spectroscopy to reveal spatial distribution of the responses in Oxy-Hb within the prefrontal cortex (PFC) during emotionally-charged audiovisual stimulation. Pleasantly-charged (comedy) stimulation caused a substantial decrease of Oxy-Hb in all regions of the PFC in 18 subjects, especially in the rostroventral frontopolar PFC, whereas negatively-charged (horror) or neutral stimulation (landscape) exhibited a weaker decrease or insignificant change in the prefrontal Oxy-Hb. In the rostral parts of the dorsolateral and ventral frontopolar PFC, the oxygenation response during comedy stimulation exhibited the most significant positive correlation with the decrease in facial skin blood flow. Thus the rostral regions of the PFC play a role in recognition and regulation of positive emotion and may be linked with neurally-mediated vasoconstriction of facial skin blood vessels. Nature Publishing Group UK 2018-09-28 /pmc/articles/PMC6162331/ /pubmed/30266925 http://dx.doi.org/10.1038/s41598-018-32752-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Matsukawa, Kanji
Asahara, Ryota
Yoshikawa, Miho
Endo, Kana
Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title_full Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title_fullStr Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title_full_unstemmed Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title_short Deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
title_sort deactivation of the prefrontal cortex during exposure to pleasantly-charged emotional challenge
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162331/
https://www.ncbi.nlm.nih.gov/pubmed/30266925
http://dx.doi.org/10.1038/s41598-018-32752-0
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