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Two-pore channels and disease()
Two-pore channels (TPCs) are Ca(2+)-permeable endo-lysosomal ion channels subject to multi-modal regulation. They mediate their physiological effects through releasing Ca(2+) from acidic organelles in response to cues such as the second messenger, NAADP. Here, we review emerging evidence linking TPC...
Autores principales: | Patel, Sandip, Kilpatrick, Bethan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162333/ https://www.ncbi.nlm.nih.gov/pubmed/29746898 http://dx.doi.org/10.1016/j.bbamcr.2018.05.004 |
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