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Capturing the applicability of in vitro-in silico membrane transporter data in chemical risk assessment and biomedical research
Costs, scientific and ethical concerns related to animal tests for regulatory decision-making have stimulated the development of alternative methods. When applying alternative approaches, kinetics have been identified as a key element to consider. Membrane transporters affect the kinetic processes o...
Autores principales: | Clerbaux, Laure-Alix, Coecke, Sandra, Lumen, Annie, Kliment, Tomas, Worth, Andrew P., Paini, Alicia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162338/ https://www.ncbi.nlm.nih.gov/pubmed/30015123 http://dx.doi.org/10.1016/j.scitotenv.2018.07.122 |
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