Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets

Salivary gland tumors are extremely rare and encompass a diverse group of histologies. Less than 5% of the affected population is pediatric. We present a case of 6-year-old child with pleomorphic adenoma of the parotid. The patient underwent a superficial parotidectomy. Recurrence was not observed i...

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Autores principales: Meshram, Girish Gulab, Kaur, Neeraj, Hura, Kanwaljeet Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162389/
https://www.ncbi.nlm.nih.gov/pubmed/30231590
http://dx.doi.org/10.3390/children5090127
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author Meshram, Girish Gulab
Kaur, Neeraj
Hura, Kanwaljeet Singh
author_facet Meshram, Girish Gulab
Kaur, Neeraj
Hura, Kanwaljeet Singh
author_sort Meshram, Girish Gulab
collection PubMed
description Salivary gland tumors are extremely rare and encompass a diverse group of histologies. Less than 5% of the affected population is pediatric. We present a case of 6-year-old child with pleomorphic adenoma of the parotid. The patient underwent a superficial parotidectomy. Recurrence was not observed in the six months of follow-up. Surgery is the mainstay of the management of benign salivary gland tumors. Although novel molecular agents are being explored, personalized therapy would be a challenge due to the rarity and vast genetic/histologic variations of salivary gland tumors.
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spelling pubmed-61623892018-10-16 Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets Meshram, Girish Gulab Kaur, Neeraj Hura, Kanwaljeet Singh Children (Basel) Case Report Salivary gland tumors are extremely rare and encompass a diverse group of histologies. Less than 5% of the affected population is pediatric. We present a case of 6-year-old child with pleomorphic adenoma of the parotid. The patient underwent a superficial parotidectomy. Recurrence was not observed in the six months of follow-up. Surgery is the mainstay of the management of benign salivary gland tumors. Although novel molecular agents are being explored, personalized therapy would be a challenge due to the rarity and vast genetic/histologic variations of salivary gland tumors. MDPI 2018-09-18 /pmc/articles/PMC6162389/ /pubmed/30231590 http://dx.doi.org/10.3390/children5090127 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Meshram, Girish Gulab
Kaur, Neeraj
Hura, Kanwaljeet Singh
Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title_full Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title_fullStr Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title_full_unstemmed Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title_short Pediatric Pleomorphic Adenoma of the Parotid: Case Report, Review of Literature and Novel Therapeutic Targets
title_sort pediatric pleomorphic adenoma of the parotid: case report, review of literature and novel therapeutic targets
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162389/
https://www.ncbi.nlm.nih.gov/pubmed/30231590
http://dx.doi.org/10.3390/children5090127
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