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RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact

RAF-kinase inhibitor protein (RKIP) is a well-established tumor suppressor that is frequently downregulated in a plethora of solid and hematological malignancies. RKIP exerts antimetastatic and pro-apoptotic properties in cancer cells, via modulation of signaling pathways and gene products involved...

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Detalles Bibliográficos
Autores principales: Zaravinos, Apostolos, Bonavida, Benjamin, Chatzaki, Ekaterini, Baritaki, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162400/
https://www.ncbi.nlm.nih.gov/pubmed/30149591
http://dx.doi.org/10.3390/cancers10090287