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RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact
RAF-kinase inhibitor protein (RKIP) is a well-established tumor suppressor that is frequently downregulated in a plethora of solid and hematological malignancies. RKIP exerts antimetastatic and pro-apoptotic properties in cancer cells, via modulation of signaling pathways and gene products involved...
Autores principales: | Zaravinos, Apostolos, Bonavida, Benjamin, Chatzaki, Ekaterini, Baritaki, Stavroula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162400/ https://www.ncbi.nlm.nih.gov/pubmed/30149591 http://dx.doi.org/10.3390/cancers10090287 |
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