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Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response
Hepatic stellate cells (HSCs) serve as the main body storage compartment for vitamin A through retinyl ester (RE)-filled lipid droplets (LDs). Upon liver injury, HSCs adopt a myofibroblastic phenotype characterized by an elevated expression of extracellular matrix proteins and a concomitant loss of...
Autores principales: | Bobowski-Gerard, Marie, Zummo, Francesco Paolo, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162435/ https://www.ncbi.nlm.nih.gov/pubmed/30217095 http://dx.doi.org/10.3390/cells7090137 |
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