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The Extracellular Matrix and Pancreatic Cancer: A Complex Relationship

Pancreatic ductal adenocarcinoma (PDAC) has an extraordinarily dense fibrotic stroma that impedes tumor perfusion and delivery of anticancer drugs. Since the extracellular matrix (ECM) comprises the bulk of the stroma, it is primarily responsible for the increased interstitial tissue pressure and st...

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Detalles Bibliográficos
Autores principales:	Weniger, Maximilian, Honselmann, Kim C., Liss, Andrew S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162452/ https://www.ncbi.nlm.nih.gov/pubmed/30200666 http://dx.doi.org/10.3390/cancers10090316

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