Cargando…

The Extracellular Matrix and Pancreatic Cancer: A Complex Relationship

Pancreatic ductal adenocarcinoma (PDAC) has an extraordinarily dense fibrotic stroma that impedes tumor perfusion and delivery of anticancer drugs. Since the extracellular matrix (ECM) comprises the bulk of the stroma, it is primarily responsible for the increased interstitial tissue pressure and st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weniger, Maximilian, Honselmann, Kim C., Liss, Andrew S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162452/ https://www.ncbi.nlm.nih.gov/pubmed/30200666 http://dx.doi.org/10.3390/cancers10090316

Ejemplares similares

The Extracellular Matrix in Pancreatic Cancer: Description of a Complex Network and Promising Therapeutic Options
por: Ferrara, Benedetta, et al.
Publicado: (2021)

Image-Based Profiling of Patient-Derived Pancreatic Tumor–Stromal Cell Interactions Within a Micropatterned Tumor Model
por: Mukundan, Shilpaa, et al.
Publicado: (2018)

Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer
por: Ahmad, Ramiz S., et al.
Publicado: (2021)

The Matrix Reloaded—The Role of the Extracellular Matrix in Cancer
por: Raskov, Hans, et al.
Publicado: (2023)

Fountain of youth of pancreatic cancer cells: the extracellular matrix
por: Gouirand, Victoire, et al.
Publicado: (2018)

Extracellular Matrix Biomarkers in Colorectal Cancer
por: Kim, Min-Seob, et al.
Publicado: (2021)

Complex mechanics of the heterogeneous extracellular matrix in cancer
por: Malandrino, Andrea, et al.
Publicado: (2018)

Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets
por: Llacua, L. Alberto, et al.
Publicado: (2018)

The Canine Pancreatic Extracellular Matrix in Diabetes Mellitus and Pancreatitis: Its Essential Role and Therapeutic Perspective
por: Pantoja, Bruna Tássia dos Santos, et al.
Publicado: (2023)

Decellularized Extracellular Matrix for Cancer Research
por: Hoshiba, Takashi
Publicado: (2019)

Extracellular matrix in cancer progression and therapy
por: He, Xiuxiu, et al.
Publicado: (2022)

Extracellular Vesicles as Regulators of the Extracellular Matrix
por: Patel, Neil J., et al.
Publicado: (2023)

The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors
por: Bolm, Louisa, et al.
Publicado: (2017)

The extracellular matrix in development
por: Walma, David A. Cruz, et al.
Publicado: (2020)

Extracellular Matrix of Echinoderms
por: Dolmatov, Igor Yu., et al.
Publicado: (2023)

Hydrogels as Extracellular Matrix Analogs
por: González-Díaz, Eva C., et al.
Publicado: (2016)

Editorial: The role of microorganisms in the development and progression of cancer
por: Weniger, Maximilian
Publicado: (2023)

Role of Extracellular Matrix in Development and Cancer Progression
por: Walker, Cameron, et al.
Publicado: (2018)

The Development of a Novel Therapeutic Strategy to Target Hyaluronan in the Extracellular Matrix of Pancreatic Ductal Adenocarcinoma
por: Kudo, Daisuke, et al.
Publicado: (2017)

The Role of Extracellular Matrix Proteins in Breast Cancer
por: Lepucki, Arkadiusz, et al.
Publicado: (2022)

The Functional Role of Extracellular Matrix Proteins in Cancer
por: Popova, Nadezhda V., et al.
Publicado: (2022)

Towards extracellular matrix normalization for improved treatment of solid tumors
por: Abyaneh, Hoda Soleymani, et al.
Publicado: (2020)

The extracellular matrix: A dynamic niche in cancer progression
por: Lu, Pengfei, et al.
Publicado: (2012)

Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance
por: Hellicar, John, et al.
Publicado: (2022)

Matrix metalloproteinase-induced cervical extracellular matrix remodelling in pregnancy and cervical cancer
por: Amabebe, Emmanuel, et al.
Publicado: (2022)

SPOCK2 gene expression is downregulated in pancreatic ductal adenocarcinoma cells and correlates with prognosis of patients with pancreatic cancer
por: Aghamaliyev, Ughur, et al.
Publicado: (2023)

Role and Evolution of the Extracellular Matrix in the Acquisition of Complex Multicellularity in Eukaryotes: A Macroalgal Perspective
por: Kloareg, Bernard, et al.
Publicado: (2021)

The Extracellular Matrix and Neuroblastoma Cell Communication—A Complex Interplay and Its Therapeutic Implications
por: Horwacik, Irena
Publicado: (2022)

Extracellular Vesicles: Interplay with the Extracellular Matrix and Modulated Cell Responses
por: Al Halawani, Aleen, et al.
Publicado: (2022)

Extracellular matrix: Forum introduction
por: Carson, Daniel D
Publicado: (2004)

The evolution of metazoan extracellular matrix
por: Hynes, Richard O.
Publicado: (2012)

Extracellular matrix remodelling in COPD
por: Karakioulaki, Meropi, et al.
Publicado: (2020)

Trends in extracellular matrix biology
por: Kyriakopoulou, Konstantina, et al.
Publicado: (2022)

Role of Extracellular Matrix in Gastrointestinal Cancer-Associated Angiogenesis
por: Andreuzzi, Eva, et al.
Publicado: (2020)

Cancer Extracellular Matrix Proteins Regulate Tumour Immunity
por: Gordon-Weeks, Alex, et al.
Publicado: (2020)

The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression
por: Moreira, Ana Margarida, et al.
Publicado: (2020)

Extracellular matrixes and neuroinflammation
por: Jang, Dong Gil, et al.
Publicado: (2020)

YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling
por: Zhou, Qimin, et al.
Publicado: (2020)

Elucidating the Role of Extracellular Vesicles in Pancreatic Cancer
por: Marzan, Akbar Lulu, et al.
Publicado: (2021)

Decellularized Extracellular Matrix: The Role of This Complex Biomaterial in Regeneration
por: de Paula, André Guilherme Portela, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cu7jdh3p69dvhf115o3sk4brcf