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Marfan Syndrome Variability: Investigation of the Roles of Sarcolipin and Calcium as Potential Transregulator of FBN1 Expression
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder that displays a great clinical variability. Previous work in our laboratory showed that fibrillin-1 (FBN1) messenger RNA (mRNA) expression is a surrogate endpoint for MFS severity. Therefore, an expression quantitative trait l...
Autores principales: | Benarroch, Louise, Aubart, Mélodie, Gross, Marie-Sylvie, Jacob, Marie-Paule, Arnaud, Pauline, Hanna, Nadine, Jondeau, Guillaume, Boileau, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162465/ https://www.ncbi.nlm.nih.gov/pubmed/30134586 http://dx.doi.org/10.3390/genes9090421 |
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