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Profiling DNA Methylation Based on Next-Generation Sequencing Approaches: New Insights and Clinical Applications
DNA methylation is an epigenetic modification that plays a pivotal role in regulating gene expression and, consequently, influences a wide variety of biological processes and diseases. The advances in next-generation sequencing technologies allow for genome-wide profiling of methyl marks both at a s...
Autores principales: | Barros-Silva, Daniela, Marques, C. Joana, Henrique, Rui, Jerónimo, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162482/ https://www.ncbi.nlm.nih.gov/pubmed/30142958 http://dx.doi.org/10.3390/genes9090429 |
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