High-Risk Neuroblastoma Treatment Review

Neuroblastoma is the most common extracranial solid tumor in children. One subset, high-risk neuroblastoma, is very difficult to treat and requires multi-modal therapy. Intensification of therapy has vastly improved survival rates, and research is focused on novel treatments to further improve survi...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Valeria, Foster, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162495/
https://www.ncbi.nlm.nih.gov/pubmed/30154341
http://dx.doi.org/10.3390/children5090114
_version_ 1783359159716020224
author Smith, Valeria
Foster, Jennifer
author_facet Smith, Valeria
Foster, Jennifer
author_sort Smith, Valeria
collection PubMed
description Neuroblastoma is the most common extracranial solid tumor in children. One subset, high-risk neuroblastoma, is very difficult to treat and requires multi-modal therapy. Intensification of therapy has vastly improved survival rates, and research is focused on novel treatments to further improve survival rates. The current treatment schema is divided into three stages—induction, consolidation, and maintenance. This review serves as an overview of the current treatment for high-risk neuroblastoma and a glimpse at current research for future therapy.
format Online
Article
Text
id pubmed-6162495
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61624952018-10-16 High-Risk Neuroblastoma Treatment Review Smith, Valeria Foster, Jennifer Children (Basel) Review Neuroblastoma is the most common extracranial solid tumor in children. One subset, high-risk neuroblastoma, is very difficult to treat and requires multi-modal therapy. Intensification of therapy has vastly improved survival rates, and research is focused on novel treatments to further improve survival rates. The current treatment schema is divided into three stages—induction, consolidation, and maintenance. This review serves as an overview of the current treatment for high-risk neuroblastoma and a glimpse at current research for future therapy. MDPI 2018-08-28 /pmc/articles/PMC6162495/ /pubmed/30154341 http://dx.doi.org/10.3390/children5090114 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Smith, Valeria
Foster, Jennifer
High-Risk Neuroblastoma Treatment Review
title High-Risk Neuroblastoma Treatment Review
title_full High-Risk Neuroblastoma Treatment Review
title_fullStr High-Risk Neuroblastoma Treatment Review
title_full_unstemmed High-Risk Neuroblastoma Treatment Review
title_short High-Risk Neuroblastoma Treatment Review
title_sort high-risk neuroblastoma treatment review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162495/
https://www.ncbi.nlm.nih.gov/pubmed/30154341
http://dx.doi.org/10.3390/children5090114
work_keys_str_mv AT smithvaleria highriskneuroblastomatreatmentreview
AT fosterjennifer highriskneuroblastomatreatmentreview

Ejemplares similares