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Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates
Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR(34)/L98H and TR(46)/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the minimal inhibitory concentr...
Autores principales: | Buil, Jochem B., Hagen, Ferry, Chowdhary, Anuradha, Verweij, Paul E., Meis, Jacques F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162657/ https://www.ncbi.nlm.nih.gov/pubmed/30158470 http://dx.doi.org/10.3390/jof4030103 |
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