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Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates

Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR(34)/L98H and TR(46)/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the minimal inhibitory concentr...

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Detalles Bibliográficos
Autores principales: Buil, Jochem B., Hagen, Ferry, Chowdhary, Anuradha, Verweij, Paul E., Meis, Jacques F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162657/
https://www.ncbi.nlm.nih.gov/pubmed/30158470
http://dx.doi.org/10.3390/jof4030103

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