Insonation of Systemically Delivered Cisplatin-Loaded Microbubbles Significantly Attenuates Nephrotoxicity of Chemotherapy in Experimental Models of Head and Neck Cancer

The use of cisplatin (CDDP), the most common chemotherapy drug for head and neck cancer, is limited by its undesirable side effects, especially nephrotoxicity. We investigated ultrasound microbubbles (USMB) as a tool to increase the local intra-tumoral CDDP level while decreasing systemic CDDP cytot...

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Detalles Bibliográficos
Autores principales: Chen, Hang-Kang, Zhang, Shu-Mei, Chang, Junn-Liang, Chen, Hsin-Chien, Lin, Yi-Chun, Shih, Cheng-Ping, Sytwu, Huey-Kang, Fang, Mei-Cho, Lin, Yuan-Yung, Kuo, Chao-Yin, Liao, Ai-Ho, Chu, Yueng-Hsiang, Wang, Chih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162676/
https://www.ncbi.nlm.nih.gov/pubmed/30189620
http://dx.doi.org/10.3390/cancers10090311

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