Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer

Hepatocyte growth factor (HGF) is the ligand for the tyrosine kinase receptor c-Met (Mesenchymal Epithelial Transition Factor also known as Hepatocyte Growth Factor Receptor, HGFR), a receptor with expression throughout epithelial and endothelial cell types. Activation of c-Met enhances cell prolife...

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Detalles Bibliográficos
Autores principales: Miranda, Oshin, Farooqui, Mariya, Siegfried, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162713/
https://www.ncbi.nlm.nih.gov/pubmed/30134579
http://dx.doi.org/10.3390/cancers10090280

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