Cariprazine, A Dopamine D(2)/D(3) Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer

Multidrug resistance (MDR) is a continuing clinical problem that limits the efficacy of chemotherapy in cancer. The over expression of the ATP-binding cassette (ABC) family G2 (ABCG2) transporter is one of the main mechanisms that mediates MDR in cancer. Molecular modeling data indicated that caripr...

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Detalles Bibliográficos
Autores principales: Hussein, Noor, Ashby, Charles R., Amawi, Haneen, Nyinawabera, Angelique, Vij, Atul, Khare, Vishwa M., Karthikeyan, Chandrabose, Tiwari, Amit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162716/
https://www.ncbi.nlm.nih.gov/pubmed/30181510
http://dx.doi.org/10.3390/cancers10090308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162716/
https://www.ncbi.nlm.nih.gov/pubmed/30181510
http://dx.doi.org/10.3390/cancers10090308

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