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The Dual Immunoregulatory function of Nlrp12 in T Cell-Mediated Immune Response: Lessons from Experimental Autoimmune Encephalomyelitis
Although the etiology of multiple sclerosis (MS) remains enigmatic, the role of T cells is unquestionably central in this pathology. Immune cells respond to pathogens and danger signals via pattern-recognition receptors (PRR). Several reports implicate Nlrp12, an intracellular PRR, in the developmen...
Autores principales: | Gharagozloo, Marjan, Mahmoud, Shaimaa, Simard, Camille, Mahvelati, Tara M., Amrani, Abdelaziz, Gris, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162721/ https://www.ncbi.nlm.nih.gov/pubmed/30150571 http://dx.doi.org/10.3390/cells7090119 |
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