Cargando…

CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt–β-catenin signaling in nucleus pulposus cells

BACKGROUND: The aims of this study were to investigate the gene expression of CCN family members in rat intervertebral disc (IVD) cells and to examine whether Wnt–β-catenin signaling regulates the expression of CCN family 2 (CCN2)/connective tissue growth factor (CTGF) in rat nucleus pulposus (NP) c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hiyama, Akihiko, Morita, Kosuke, Sakai, Daisuke, Watanabe, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162946/ https://www.ncbi.nlm.nih.gov/pubmed/30268161 http://dx.doi.org/10.1186/s13075-018-1723-8

Ejemplares similares

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc
por: Oh, Chun-do, et al.
Publicado: (2016)

Role of Matricellular CCN Proteins in Skeletal Muscle: Focus on CCN2/CTGF and Its Regulation by Vasoactive Peptides
por: Rebolledo, Daniela L., et al.
Publicado: (2021)

A potential role for CCN2/CTGF in aggressive colorectal cancer
por: Ubink, Inge, et al.
Publicado: (2016)

CCN2/CTGF promotor activity in the developing and adult mouse eye
por: Dillinger, Andrea E., et al.
Publicado: (2021)

CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte
por: Dillinger, Andrea E., et al.
Publicado: (2022)

Cartilage–Specific Over-Expression of CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Stimulates Insulin-Like Growth Factor Expression and Bone Growth
por: Tomita, Nao, et al.
Publicado: (2013)

CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Has Anti-Aging Effects That Protect Articular Cartilage from Age-Related Degenerative Changes
por: Itoh, Shinsuke, et al.
Publicado: (2013)

Dynamic Malignant Wave of Ribosome-Insulted Gut Niche via the Wnt-CTGF/CCN2 Circuit
por: Kim, Ki Hyung, et al.
Publicado: (2020)

New strategy to control cell migration and metastasis regulated by CCN2/CTGF
por: Aguiar, Diego Pinheiro, et al.
Publicado: (2014)

Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy
por: Wang, Songyan, et al.
Publicado: (2015)

Global expression profiling reveals regulation of CTGF/CCN2 during lactogenic differentiation
por: Wang, Weihan, et al.
Publicado: (2009)

Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
por: Brigstock, David R.
Publicado: (2009)

Connective Tissue Growth Factor (CTGF/CCN2) Is Negatively Regulated during Neuron-Glioblastoma Interaction
por: Romão, Luciana F., et al.
Publicado: (2013)

Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF)
por: Rebolledo, Daniela L., et al.
Publicado: (2021)

CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling
por: Pi, Liya, et al.
Publicado: (2022)

Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review
por: Volleman, Tibo Nico Emmie, et al.
Publicado: (2020)

Differential expression of CCN family members CYR611, CTGF and NOV in gastric cancer and their association with disease progression
por: Li, Jun, et al.
Publicado: (2016)

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system
por: Malik, Anna R., et al.
Publicado: (2015)

The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells
por: Hiyama, Akihiko, et al.
Publicado: (2012)

A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells
por: Hiyama, Akihiko, et al.
Publicado: (2013)

The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation
por: Erwin, W. Mark
Publicado: (2008)

CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury
por: Kaasbøll, Ole Jørgen, et al.
Publicado: (2016)

Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells
por: Xiao, Kang, et al.
Publicado: (2022)

Development of Normal and Cleft Palate: A Central Role for Connective Tissue Growth Factor (CTGF)/CCN2
por: Tarr, Joseph T., et al.
Publicado: (2018)

The skinny on CCN2
por: Leask, Andrew
Publicado: (2008)

A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis
por: Planque, Nathalie, et al.
Publicado: (2003)

CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress
por: Hall-Glenn, Faith, et al.
Publicado: (2013)

Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
por: Ercan, Ebru, et al.
Publicado: (2017)

Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells
por: Asano, Masahiro, et al.
Publicado: (2005)

Ets-1 Is Essential for Connective Tissue Growth Factor (CTGF/CCN2) Induction by TGF-β1 in Osteoblasts
por: Geisinger, Max T., et al.
Publicado: (2012)

Antiproliferative factor regulates connective tissue growth factor (CTGF/CCN2) expression in T24 bladder carcinoma cells
por: Matika, Christina A., et al.
Publicado: (2012)

Myocardial Connective Tissue Growth Factor (CCN2/CTGF) Attenuates Left Ventricular Remodeling after Myocardial Infarction
por: Gravning, Jørgen, et al.
Publicado: (2012)

Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro
por: Mendes, Fabio A., et al.
Publicado: (2015)

Minimal Sustainability of Dedifferentiation by ROCK Inhibitor on Rat Nucleus Pulposus Cells In Vitro
por: Nukaga, Tadashi, et al.
Publicado: (2019)

Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes
por: Wang, Xiaoyu, et al.
Publicado: (2010)

Yin/Yang expression of CCN family members: Transforming growth factor beta 1, via ALK5/FAK/MEK, induces CCN1 and CCN2, yet suppresses CCN3, expression in human dermal fibroblasts
por: Peidl, Alexander, et al.
Publicado: (2019)

Yin and Yang: CCN3 inhibits the pro-fibrotic effects of CCN2
por: Leask, Andrew
Publicado: (2009)

Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury
por: Barbe, Mary F., et al.
Publicado: (2020)

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?
por: Leask, Andrew, et al.
Publicado: (2009)

Integrin Mediated Adhesion of Osteoblasts to Connective Tissue Growth Factor (CTGF/CCN2) Induces Cytoskeleton Reorganization and Cell Differentiation
por: Hendesi, Honey, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_k0nab2t20qf15n6urskbjpfbj6