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The frequency of TP53 R72P and MDM2 309T>G polymorphisms in Iranian infertile men with spermatogenetic failure: A case-control study

BACKGROUND: Tumor protein p53 (TP53) is a tumor suppressor transcriptional regulator protein which plays a critical role in the spermatogenesis. One of the most important regulators of p53 is Murine double minute 2 (MDM2), which acts as a negative regulator of the p53 pathway. Based on the key role...

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Detalles Bibliográficos
Autores principales: Ebrahim Abadi, Zeinab, Khademi Bami, Maryam, Golzadeh, Maryam, Kalantar, Seyed Mehdi, Sheikhha, Mohammad Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Clinical Center for Infertility 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163049/
https://www.ncbi.nlm.nih.gov/pubmed/30288482

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