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Inflammatory mediators reduce surface PrP(c) on human BMVEC resulting in decreased barrier integrity

The cellular prion protein (PrP(c)) is a surface adhesion molecule expressed at junctions of various cell types including brain microvascular endothelial cells (BMVEC) that are important components of the blood brain barrier (BBB). PrP(c) is involved in several physiological processes including regu...

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Detalles Bibliográficos
Autores principales:	Megra, Bezawit W., Eugenin, Eliseo A., Berman, Joan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163073/ https://www.ncbi.nlm.nih.gov/pubmed/29959417 http://dx.doi.org/10.1038/s41374-018-0090-z

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