Cargando…

Bacteriophages: Protagonists of a Post-Antibiotic Era

Despite their long success for more than half a century, antibiotics are currently under the spotlight due to the emergence of multidrug-resistant bacteria. The development of new alternative treatments is of particular interest in the fight against bacterial resistance. Bacteriophages (phages) are...

Descripción completa

Detalles Bibliográficos
Autores principales: Domingo-Calap, Pilar, Delgado-Martínez, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163168/
https://www.ncbi.nlm.nih.gov/pubmed/30060506
http://dx.doi.org/10.3390/antibiotics7030066
_version_ 1783359295933382656
author Domingo-Calap, Pilar
Delgado-Martínez, Jennifer
author_facet Domingo-Calap, Pilar
Delgado-Martínez, Jennifer
author_sort Domingo-Calap, Pilar
collection PubMed
description Despite their long success for more than half a century, antibiotics are currently under the spotlight due to the emergence of multidrug-resistant bacteria. The development of new alternative treatments is of particular interest in the fight against bacterial resistance. Bacteriophages (phages) are natural killers of bacteria and are an excellent tool due to their specificity and ecological safety. Here, we highlight some of their advantages and drawbacks as potential therapeutic agents. Interestingly, phages are not only attractive from a clinical point of view, but other areas, such as agriculture, food control, or industry, are also areas for their potential application. Therefore, we propose phages as a real alternative to current antibiotics.
format Online
Article
Text
id pubmed-6163168
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61631682018-10-12 Bacteriophages: Protagonists of a Post-Antibiotic Era Domingo-Calap, Pilar Delgado-Martínez, Jennifer Antibiotics (Basel) Review Despite their long success for more than half a century, antibiotics are currently under the spotlight due to the emergence of multidrug-resistant bacteria. The development of new alternative treatments is of particular interest in the fight against bacterial resistance. Bacteriophages (phages) are natural killers of bacteria and are an excellent tool due to their specificity and ecological safety. Here, we highlight some of their advantages and drawbacks as potential therapeutic agents. Interestingly, phages are not only attractive from a clinical point of view, but other areas, such as agriculture, food control, or industry, are also areas for their potential application. Therefore, we propose phages as a real alternative to current antibiotics. MDPI 2018-07-27 /pmc/articles/PMC6163168/ /pubmed/30060506 http://dx.doi.org/10.3390/antibiotics7030066 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Domingo-Calap, Pilar
Delgado-Martínez, Jennifer
Bacteriophages: Protagonists of a Post-Antibiotic Era
title Bacteriophages: Protagonists of a Post-Antibiotic Era
title_full Bacteriophages: Protagonists of a Post-Antibiotic Era
title_fullStr Bacteriophages: Protagonists of a Post-Antibiotic Era
title_full_unstemmed Bacteriophages: Protagonists of a Post-Antibiotic Era
title_short Bacteriophages: Protagonists of a Post-Antibiotic Era
title_sort bacteriophages: protagonists of a post-antibiotic era
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163168/
https://www.ncbi.nlm.nih.gov/pubmed/30060506
http://dx.doi.org/10.3390/antibiotics7030066
work_keys_str_mv AT domingocalappilar bacteriophagesprotagonistsofapostantibioticera
AT delgadomartinezjennifer bacteriophagesprotagonistsofapostantibioticera