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Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

The repair of focal articular cartilage defects remains a problem. Combining gene therapy with tissue engineering approaches using bone marrow-derived mesenchymal stem cells (MSCs) may allow the development of improved options for cartilage repair. Here, we examined whether a three-dimensional fibri...

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Detalles Bibliográficos
Autores principales: Venkatesan, Jagadeesh K., Gardner, Oliver, Rey-Rico, Ana, Eglin, David, Alini, Mauro, Stoddart, Martin J., Cucchiarini, Magali, Madry, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163252/
https://www.ncbi.nlm.nih.gov/pubmed/30189664
http://dx.doi.org/10.3390/ijms19092635

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