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Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment
The repair of focal articular cartilage defects remains a problem. Combining gene therapy with tissue engineering approaches using bone marrow-derived mesenchymal stem cells (MSCs) may allow the development of improved options for cartilage repair. Here, we examined whether a three-dimensional fibri...
Autores principales: | Venkatesan, Jagadeesh K., Gardner, Oliver, Rey-Rico, Ana, Eglin, David, Alini, Mauro, Stoddart, Martin J., Cucchiarini, Magali, Madry, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163252/ https://www.ncbi.nlm.nih.gov/pubmed/30189664 http://dx.doi.org/10.3390/ijms19092635 |
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