Cargando…
Actin-Myosin Interaction: Structure, Function and Drug Discovery
Actin-myosin interactions play crucial roles in the generation of cellular force and movement. The molecular mechanism involves structural transitions at the interface between actin and myosin’s catalytic domain, and within myosin’s light chain domain, which contains binding sites for essential (ELC...
Autores principales: | Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163256/ https://www.ncbi.nlm.nih.gov/pubmed/30189615 http://dx.doi.org/10.3390/ijms19092628 |
Ejemplares similares
-
Drug discovery for heart failure targeting myosin-binding protein C
por: Bunch, Thomas A., et al.
Publicado: (2023) -
Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen
por: Bunch, Thomas A., et al.
Publicado: (2021) -
Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5
por: Guhathakurta, Piyali, et al.
Publicado: (2023) -
Myosins, Actin and Autophagy
por: Kruppa, Antonina J., et al.
Publicado: (2016) -
Calcium inhibition as an intracellular signal for actin–myosin interaction
por: KOHAMA, Kazuhiro
Publicado: (2016)