DnaG Primase—A Target for the Development of Novel Antibacterial Agents

The bacterial primase—an essential component in the replisome—is a promising but underexploited target for novel antibiotic drugs. Bacterial primases have a markedly different structure than the human primase. Inhibition of primase activity is expected to selectively halt bacterial DNA replication....

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Detalles Bibliográficos
Autores principales: Ilic, Stefan, Cohen, Shira, Singh, Meenakshi, Tam, Benjamin, Dayan, Adi, Akabayov, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163395/
https://www.ncbi.nlm.nih.gov/pubmed/30104489
http://dx.doi.org/10.3390/antibiotics7030072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163395/
https://www.ncbi.nlm.nih.gov/pubmed/30104489
http://dx.doi.org/10.3390/antibiotics7030072

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