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DnaG Primase—A Target for the Development of Novel Antibacterial Agents
The bacterial primase—an essential component in the replisome—is a promising but underexploited target for novel antibiotic drugs. Bacterial primases have a markedly different structure than the human primase. Inhibition of primase activity is expected to selectively halt bacterial DNA replication....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163395/ https://www.ncbi.nlm.nih.gov/pubmed/30104489 http://dx.doi.org/10.3390/antibiotics7030072 |