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β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides

The ability of cell penetrating peptides (CPPs) to deliver biologically relevant cargos into cells is becoming more important as targets in the intracellular space continue to be explored. We have developed two assays based on CPP-dependent, intracellular delivery of TEM-1 β-lactamase enzyme, a func...

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Detalles Bibliográficos
Autores principales: Stone, Shane R., Heinrich, Tatjana, Juraja, Suzy M., Satiaputra, Jiulia N., Hall, Clinton M., Anastasas, Mark, Mills, Anna D., Chamberlain, Christopher A., Winslow, Scott, Priebatsch, Kristin, Cunningham, Paula T., Hoffmann, Katrin, Milech, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163455/
https://www.ncbi.nlm.nih.gov/pubmed/29997382
http://dx.doi.org/10.3390/biom8030051