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Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma
Glioblastoma remains a fatal diagnosis. Previous research has shown that metformin, which is an inhibitor of complex I of the respiratory chain, may inhibit some brain tumor initiating cells (BTICs), albeit at dosages that are too high for clinical use. Here, we explored whether a combined treatment...
Autores principales: | Gerthofer, Valeria, Kreutz, Marina, Renner, Kathrin, Jachnik, Birgit, Dettmer, Katja, Oefner, Peter, Riemenschneider, Markus J., Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163514/ https://www.ncbi.nlm.nih.gov/pubmed/30200299 http://dx.doi.org/10.3390/ijms19092586 |
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