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TOP2B: The First Thirty Years

Type II DNA topoisomerases (EC 5.99.1.3) are enzymes that catalyse topological changes in DNA in an ATP dependent manner. Strand passage reactions involve passing one double stranded DNA duplex (transported helix) through a transient enzyme-bridged break in another (gated helix). This activity is re...

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Detalles Bibliográficos
Autores principales:	Austin, Caroline A., Lee, Ka C., Swan, Rebecca L., Khazeem, Mushtaq M., Manville, Catriona M., Cridland, Peter, Treumann, Achim, Porter, Andrew, Morris, Nick J., Cowell, Ian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163646/ https://www.ncbi.nlm.nih.gov/pubmed/30223465 http://dx.doi.org/10.3390/ijms19092765

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