Cargando…

Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction

Melatonin is the main pineal hormone that relays light/dark-cycle information to the circadian system. Recent studies have examined the intrinsic antitumor activity of melatonin in various cancers, including hepatocellular carcinoma (HCC), the primary life-threatening malignancy in both sexes in Tai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Tong-Hong, Hsueh, Chuen, Chen, Chin-Chuan, Li, Wan-Syuan, Yeh, Chau-Ting, Lian, Jang-Hau, Chang, Junn-Liang, Chen, Chi-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163650/ https://www.ncbi.nlm.nih.gov/pubmed/30201903 http://dx.doi.org/10.3390/ijms19092687

Ejemplares similares

Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation
por: Wang, Tong-Hong, et al.
Publicado: (2017)

Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair
por: Chen, Chin-Chuan, et al.
Publicado: (2018)

Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5
por: Chen, Chi-Yuan, et al.
Publicado: (2018)

Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair
por: Chen, Chin-Chuan, et al.
Publicado: (2018)

Overexpression of microRNA let-7 correlates with disease progression and poor prognosis in hepatocellular carcinoma
por: Shi, Wenxia, et al.
Publicado: (2017)

Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells
por: Chen, Chi-Yuan, et al.
Publicado: (2020)

Radiosensitization of Hepatocellular Carcinoma through Targeting Radio-Associated MicroRNA
por: Wu, Cheng-Heng, et al.
Publicado: (2020)

RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition
por: Jin, Ting, et al.
Publicado: (2017)

Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition
por: Wang, Tong-Hong, et al.
Publicado: (2015)

Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell-derived neurotrophic factor expression
por: Tiong, Yee Lian, et al.
Publicado: (2020)

A Combination of Let-7d, Let-7g and Let-7i Serves as a Stable Reference for Normalization of Serum microRNAs
por: Chen, Xi, et al.
Publicado: (2013)

Long noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymal transition
por: Wang, Tong-Hong, et al.
Publicado: (2016)

Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells
por: Jin, Huajun, et al.
Publicado: (2011)

The mechanism of Raf activation through dimerization
por: Zhang, Mingzhen, et al.
Publicado: (2021)

Serum microRNA let-7a-1/let-7d/let-7f and miRNA 143/145 Gene Expression Profiles as Potential Biomarkers in HCV Induced Hepatocellular Carcinoma
por: Aly, Doaa Mamdouh, et al.
Publicado: (2020)

Melatonin, coronavirus, cardiovascular disease, and the geriatric emergency: let's use everything we have!
por: Domínguez-Rodríguez, Alberto, et al.
Publicado: (2020)

Let-7 microRNAs and Opioid Tolerance
por: He, Ying, et al.
Publicado: (2012)

Evolution of the let-7 microRNA Family
por: Hertel, Jana, et al.
Publicado: (2012)

Targeting the Raf kinases in human cancer: the Raf dimer dilemma
por: Durrant, David E, et al.
Publicado: (2018)

Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression
por: Chou, Li-Fang, et al.
Publicado: (2019)

Identification of Postoperative Prognostic MicroRNA Predictors in Hepatocellular Carcinoma
por: Huang, Ya-Hui, et al.
Publicado: (2012)

MicroRNA let-7b inhibits cell proliferation via upregulation of p21 in hepatocellular carcinoma
por: Hui, Li, et al.
Publicado: (2020)

RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans
por: Chu, Yu-De, et al.
Publicado: (2014)

Melatonin, coronavirus, cardiovascular disease, and the geriatric emergency: let's use everything we have! Response
por: García-Blas, Sergio, et al.
Publicado: (2020)

“RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway
por: Cseh, Botond, et al.
Publicado: (2014)

Psorachromene Suppresses Oral Squamous Cell Carcinoma Progression by Inhibiting Long Non-coding RNA GAS5 Mediated Epithelial-Mesenchymal Transition
por: Wang, Tong-Hong, et al.
Publicado: (2019)

MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c
por: Gururajan, A, et al.
Publicado: (2016)

Melatonin inhibiting the survival of human gastric cancer cells under ER stress involving autophagy and Ras‐Raf‐MAPK signalling
por: Huang, Yongye, et al.
Publicado: (2020)

Mutant K-ras oncogene regulates steroidogenesis of normal human adrenocortical cells by the RAF-MEK-MAPK pathway
por: Wu, C-H, et al.
Publicado: (2002)

MicroRNA Let-7adf in Tet regulation
por: Jiang, Shuai
Publicado: (2019)

MicroRNA Let-7 in B lymphocyte activation
por: Jiang, Shuai, et al.
Publicado: (2019)

SALL4 and microRNA: The Role of Let-7
por: Liu, Jun, et al.
Publicado: (2021)

UHRF2 promotes Hepatocellular Carcinoma Progression by Upregulating ErbB3/Ras/Raf Signaling Pathway
por: Sun, Jingjie, et al.
Publicado: (2021)

Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma
por: Hill, Brianne, et al.
Publicado: (2014)

2-O-Methylmagnolol, a Magnolol Derivative, Suppresses Hepatocellular Carcinoma Progression via Inhibiting Class I Histone Deacetylase Expression
por: Chen, Chi-Yuan, et al.
Publicado: (2020)

Reexpression of Let-7g MicroRNA Inhibits the Proliferation and Migration via K-Ras/HMGA2/Snail Axis in Hepatocellular Carcinoma
por: Chen, Ke-ji, et al.
Publicado: (2014)

Roles of Thyroid Hormone-Associated microRNAs Affecting Oxidative Stress in Human Hepatocellular Carcinoma
por: Huang, Po-Shuan, et al.
Publicado: (2019)

Advances in the application of Let-7 microRNAs in the diagnosis, treatment and prognosis of leukemia
por: Chen, Hao, et al.
Publicado: (2022)

The Reduction in Circulating Melatonin Level May Contribute to the Pathogenesis of Ovarian Cancer: A Retrospective Study
por: Zhao, Min, et al.
Publicado: (2016)

Microrna let-7: an emerging next-generation cancer therapeutic
por: Barh, D., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_k6ol1th9tirtli5q19u1shf9ek