Research Progress on the Relationship between Atherosclerosis and Inflammation

Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute cardiovascular disease. Atherosclerosis-related inflammation is mediated by proinflammatory cytokines, inflammatory...

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Autores principales: Zhu, Yuhua, Xian, Xuemei, Wang, Zhenzhen, Bi, Yingchao, Chen, Quangang, Han, Xufeng, Tang, Daoquan, Chen, Renjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163673/
https://www.ncbi.nlm.nih.gov/pubmed/30142970
http://dx.doi.org/10.3390/biom8030080
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author Zhu, Yuhua
Xian, Xuemei
Wang, Zhenzhen
Bi, Yingchao
Chen, Quangang
Han, Xufeng
Tang, Daoquan
Chen, Renjin
author_facet Zhu, Yuhua
Xian, Xuemei
Wang, Zhenzhen
Bi, Yingchao
Chen, Quangang
Han, Xufeng
Tang, Daoquan
Chen, Renjin
author_sort Zhu, Yuhua
collection PubMed
description Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute cardiovascular disease. Atherosclerosis-related inflammation is mediated by proinflammatory cytokines, inflammatory signaling pathways, bioactive lipids, and adhesion molecules. This review discusses the effects of inflammation and the systemic inflammatory signaling pathway on atherosclerosis, the role of related signaling pathways in inflammation, the formation of atherosclerosis plaques, and the prospects of treating atherosclerosis by inhibiting inflammation.
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spelling pubmed-61636732018-10-10 Research Progress on the Relationship between Atherosclerosis and Inflammation Zhu, Yuhua Xian, Xuemei Wang, Zhenzhen Bi, Yingchao Chen, Quangang Han, Xufeng Tang, Daoquan Chen, Renjin Biomolecules Review Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute cardiovascular disease. Atherosclerosis-related inflammation is mediated by proinflammatory cytokines, inflammatory signaling pathways, bioactive lipids, and adhesion molecules. This review discusses the effects of inflammation and the systemic inflammatory signaling pathway on atherosclerosis, the role of related signaling pathways in inflammation, the formation of atherosclerosis plaques, and the prospects of treating atherosclerosis by inhibiting inflammation. MDPI 2018-08-23 /pmc/articles/PMC6163673/ /pubmed/30142970 http://dx.doi.org/10.3390/biom8030080 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhu, Yuhua
Xian, Xuemei
Wang, Zhenzhen
Bi, Yingchao
Chen, Quangang
Han, Xufeng
Tang, Daoquan
Chen, Renjin
Research Progress on the Relationship between Atherosclerosis and Inflammation
title Research Progress on the Relationship between Atherosclerosis and Inflammation
title_full Research Progress on the Relationship between Atherosclerosis and Inflammation
title_fullStr Research Progress on the Relationship between Atherosclerosis and Inflammation
title_full_unstemmed Research Progress on the Relationship between Atherosclerosis and Inflammation
title_short Research Progress on the Relationship between Atherosclerosis and Inflammation
title_sort research progress on the relationship between atherosclerosis and inflammation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163673/
https://www.ncbi.nlm.nih.gov/pubmed/30142970
http://dx.doi.org/10.3390/biom8030080
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