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Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae

Haematococcus pluvialis microalgae in the red phase can produce significant amounts of astaxanthin, lutein, and fatty acids (FAs), which are valuable antioxidants in nutraceutics and cosmetics. Extraction of astaxanthin, lutein, and FAs from disrupted biomass of the H. pluvialis red phase using carb...

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Autores principales: Sanzo, Giuseppe Di, Mehariya, Sanjeet, Martino, Maria, Larocca, Vincenzo, Casella, Patrizia, Chianese, Simeone, Musmarra, Dino, Balducchi, Roberto, Molino, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163853/
https://www.ncbi.nlm.nih.gov/pubmed/30217068
http://dx.doi.org/10.3390/md16090334
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author Sanzo, Giuseppe Di
Mehariya, Sanjeet
Martino, Maria
Larocca, Vincenzo
Casella, Patrizia
Chianese, Simeone
Musmarra, Dino
Balducchi, Roberto
Molino, Antonio
author_facet Sanzo, Giuseppe Di
Mehariya, Sanjeet
Martino, Maria
Larocca, Vincenzo
Casella, Patrizia
Chianese, Simeone
Musmarra, Dino
Balducchi, Roberto
Molino, Antonio
author_sort Sanzo, Giuseppe Di
collection PubMed
description Haematococcus pluvialis microalgae in the red phase can produce significant amounts of astaxanthin, lutein, and fatty acids (FAs), which are valuable antioxidants in nutraceutics and cosmetics. Extraction of astaxanthin, lutein, and FAs from disrupted biomass of the H. pluvialis red phase using carbon dioxide (CO(2)) in supercritical fluid extraction (SFE) conditions was investigated using a bench-scale reactor in a semi-batch configuration. In particular, the effect of extraction time (20, 40, 60, 80, and 120 min), CO(2) flow rate (3.62 and 14.48 g/min) temperature (50, 65, and 80 °C), and pressure (100, 400, and 550 bar.) was explored. The results show the maximum recovery of astaxanthin and lutein achieved were 98.6% and 52.3%, respectively, at 50 °C and 550 bars, while the maximum recovery of FAs attained was 93.2% at 65 °C and 550 bars.
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spelling pubmed-61638532018-10-11 Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae Sanzo, Giuseppe Di Mehariya, Sanjeet Martino, Maria Larocca, Vincenzo Casella, Patrizia Chianese, Simeone Musmarra, Dino Balducchi, Roberto Molino, Antonio Mar Drugs Article Haematococcus pluvialis microalgae in the red phase can produce significant amounts of astaxanthin, lutein, and fatty acids (FAs), which are valuable antioxidants in nutraceutics and cosmetics. Extraction of astaxanthin, lutein, and FAs from disrupted biomass of the H. pluvialis red phase using carbon dioxide (CO(2)) in supercritical fluid extraction (SFE) conditions was investigated using a bench-scale reactor in a semi-batch configuration. In particular, the effect of extraction time (20, 40, 60, 80, and 120 min), CO(2) flow rate (3.62 and 14.48 g/min) temperature (50, 65, and 80 °C), and pressure (100, 400, and 550 bar.) was explored. The results show the maximum recovery of astaxanthin and lutein achieved were 98.6% and 52.3%, respectively, at 50 °C and 550 bars, while the maximum recovery of FAs attained was 93.2% at 65 °C and 550 bars. MDPI 2018-09-13 /pmc/articles/PMC6163853/ /pubmed/30217068 http://dx.doi.org/10.3390/md16090334 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sanzo, Giuseppe Di
Mehariya, Sanjeet
Martino, Maria
Larocca, Vincenzo
Casella, Patrizia
Chianese, Simeone
Musmarra, Dino
Balducchi, Roberto
Molino, Antonio
Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title_full Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title_fullStr Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title_full_unstemmed Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title_short Supercritical Carbon Dioxide Extraction of Astaxanthin, Lutein, and Fatty Acids from Haematococcus pluvialis Microalgae
title_sort supercritical carbon dioxide extraction of astaxanthin, lutein, and fatty acids from haematococcus pluvialis microalgae
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163853/
https://www.ncbi.nlm.nih.gov/pubmed/30217068
http://dx.doi.org/10.3390/md16090334
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