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Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications
Biocompatible titanium scaffolds with up to 40% interconnected porosity were manufactured through the metal injection moulding process and the space holder technique. The mechanical properties of the manufactured scaffold showed a high level of compatibility with those of the cortical human bone. Si...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163891/ https://www.ncbi.nlm.nih.gov/pubmed/30200402 http://dx.doi.org/10.3390/ma11091573 |
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author | Dehghan-Manshadi, Ali Chen, Yunhui Shi, Zhiming Bermingham, Michael StJohn, David Dargusch, Matthew Qian, Ma |
author_facet | Dehghan-Manshadi, Ali Chen, Yunhui Shi, Zhiming Bermingham, Michael StJohn, David Dargusch, Matthew Qian, Ma |
author_sort | Dehghan-Manshadi, Ali |
collection | PubMed |
description | Biocompatible titanium scaffolds with up to 40% interconnected porosity were manufactured through the metal injection moulding process and the space holder technique. The mechanical properties of the manufactured scaffold showed a high level of compatibility with those of the cortical human bone. Sintering at 1250 °C produced scaffolds with 36% porosity and more than 90% interconnected pores, a compressive yield stress of 220 MPa and a Young’s modulus of 7.80 GPa, all suitable for bone tissue engineering. Increasing the sintering temperature to 1300 °C increased the Young’s modulus to 22.0 GPa due to reduced porosity, while reducing the sintering temperature to 1150 °C lowered the yield stress to 120 MPa, indicative of insufficient sintering. Electrochemical studies revealed that samples sintered at 1150 °C have a higher corrosion rate compared with those at a sintering temperature of 1250 °C. Overall, it was concluded that sintering at 1250 °C yielded the most desirable results. |
format | Online Article Text |
id | pubmed-6163891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61638912018-10-12 Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications Dehghan-Manshadi, Ali Chen, Yunhui Shi, Zhiming Bermingham, Michael StJohn, David Dargusch, Matthew Qian, Ma Materials (Basel) Article Biocompatible titanium scaffolds with up to 40% interconnected porosity were manufactured through the metal injection moulding process and the space holder technique. The mechanical properties of the manufactured scaffold showed a high level of compatibility with those of the cortical human bone. Sintering at 1250 °C produced scaffolds with 36% porosity and more than 90% interconnected pores, a compressive yield stress of 220 MPa and a Young’s modulus of 7.80 GPa, all suitable for bone tissue engineering. Increasing the sintering temperature to 1300 °C increased the Young’s modulus to 22.0 GPa due to reduced porosity, while reducing the sintering temperature to 1150 °C lowered the yield stress to 120 MPa, indicative of insufficient sintering. Electrochemical studies revealed that samples sintered at 1150 °C have a higher corrosion rate compared with those at a sintering temperature of 1250 °C. Overall, it was concluded that sintering at 1250 °C yielded the most desirable results. MDPI 2018-09-01 /pmc/articles/PMC6163891/ /pubmed/30200402 http://dx.doi.org/10.3390/ma11091573 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Dehghan-Manshadi, Ali Chen, Yunhui Shi, Zhiming Bermingham, Michael StJohn, David Dargusch, Matthew Qian, Ma Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title | Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title_full | Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title_fullStr | Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title_full_unstemmed | Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title_short | Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications |
title_sort | porous titanium scaffolds fabricated by metal injection moulding for biomedical applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163891/ https://www.ncbi.nlm.nih.gov/pubmed/30200402 http://dx.doi.org/10.3390/ma11091573 |
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