Cargando…
In Vivo Genome Editing as a Therapeutic Approach
Genome editing has been well established as a genome engineering tool that enables researchers to establish causal linkages between genetic mutation and biological phenotypes, providing further understanding of the genetic manifestation of many debilitating diseases. More recently, the paradigm of g...
Autores principales: | Ho, Beatrice Xuan, Loh, Sharon Jia Hui, Chan, Woon Khiong, Soh, Boon Seng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163904/ https://www.ncbi.nlm.nih.gov/pubmed/30213032 http://dx.doi.org/10.3390/ijms19092721 |
Ejemplares similares
-
Insights to Heart Development and Cardiac Disease Models Using Pluripotent Stem Cell Derived 3D Organoids
por: Pang, Jeremy Kah Sheng, et al.
Publicado: (2021) -
Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing
por: Han, Hua Alexander, et al.
Publicado: (2020) -
Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases
por: Ho, Beatrice Xuan, et al.
Publicado: (2022) -
Mending a broken heart: current strategies and limitations of cell-based therapy
por: Liew, Lee Chuen, et al.
Publicado: (2020) -
In Vivo Delivery Systems for Therapeutic Genome Editing
por: Wang, Luyao, et al.
Publicado: (2016)