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Lysoquinone-TH1, a New Polyphenolic Tridecaketide Produced by Expressing the Lysolipin Minimal PKS II in Streptomyces albus

The structural repertoire of bioactive naphthacene quinones is expanded by engineering Streptomyces albus to express the lysolipin minimal polyketide synthase II (PKS II) genes from Streptomyces tendae Tü 4042 (llpD-F) with the corresponding cyclase genes llpCI-CIII. Fermentation of the recombinant...

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Detalles Bibliográficos
Autores principales:	Hofeditz, Torben, Unsin, Claudia Eva-Maria, Wiese, Jutta, Imhoff, Johannes F., Wohlleben, Wolfgang, Grond, Stephanie, Weber, Tilmann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164072/ https://www.ncbi.nlm.nih.gov/pubmed/29958422 http://dx.doi.org/10.3390/antibiotics7030053

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