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Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil

The outbreak of Zika virus in Latin America in the period 2015–2016 has caused a sudden increase in the number of severe manifestations and reports of congenital changes in newborns in Brazil. This is the first study that evaluated and compared the growth and cognitive and motor development of child...

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Autores principales: de França, Thaís Lorena Barbosa, Medeiros, Wilton Rodrigues, de Souza, Nilba Lima, Longo, Egmar, Pereira, Silvana Alves, França, Thamyris Barbosa de Oliveira, Sousa, Klayton Galante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164092/
https://www.ncbi.nlm.nih.gov/pubmed/30216976
http://dx.doi.org/10.3390/ijerph15091990
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author de França, Thaís Lorena Barbosa
Medeiros, Wilton Rodrigues
de Souza, Nilba Lima
Longo, Egmar
Pereira, Silvana Alves
França, Thamyris Barbosa de Oliveira
Sousa, Klayton Galante
author_facet de França, Thaís Lorena Barbosa
Medeiros, Wilton Rodrigues
de Souza, Nilba Lima
Longo, Egmar
Pereira, Silvana Alves
França, Thamyris Barbosa de Oliveira
Sousa, Klayton Galante
author_sort de França, Thaís Lorena Barbosa
collection PubMed
description The outbreak of Zika virus in Latin America in the period 2015–2016 has caused a sudden increase in the number of severe manifestations and reports of congenital changes in newborns in Brazil. This is the first study that evaluated and compared the growth and cognitive and motor development of children with microcephaly due to Congenital Zika Virus Syndrome (CZS) in relation to typical children. It was an observational, analytical, cross-sectional study with 8 children with CZS and 16 typical children, with a mean age of 20.5 months (±2.1), in a region of northeastern Brazil. Considering the mean, children with CZS presented extremely low performance in the motor domain and in the cognitive development domain, whereas typical children presented average performance in the cognitive and motor development domains. Children with CZS presented a mean growth rate (head circumference and weight) lower than typical children. Therefore, children with CZS are at risk for growth retardation and development compared to typical children.
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spelling pubmed-61640922018-10-12 Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil de França, Thaís Lorena Barbosa Medeiros, Wilton Rodrigues de Souza, Nilba Lima Longo, Egmar Pereira, Silvana Alves França, Thamyris Barbosa de Oliveira Sousa, Klayton Galante Int J Environ Res Public Health Article The outbreak of Zika virus in Latin America in the period 2015–2016 has caused a sudden increase in the number of severe manifestations and reports of congenital changes in newborns in Brazil. This is the first study that evaluated and compared the growth and cognitive and motor development of children with microcephaly due to Congenital Zika Virus Syndrome (CZS) in relation to typical children. It was an observational, analytical, cross-sectional study with 8 children with CZS and 16 typical children, with a mean age of 20.5 months (±2.1), in a region of northeastern Brazil. Considering the mean, children with CZS presented extremely low performance in the motor domain and in the cognitive development domain, whereas typical children presented average performance in the cognitive and motor development domains. Children with CZS presented a mean growth rate (head circumference and weight) lower than typical children. Therefore, children with CZS are at risk for growth retardation and development compared to typical children. MDPI 2018-09-13 2018-09 /pmc/articles/PMC6164092/ /pubmed/30216976 http://dx.doi.org/10.3390/ijerph15091990 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de França, Thaís Lorena Barbosa
Medeiros, Wilton Rodrigues
de Souza, Nilba Lima
Longo, Egmar
Pereira, Silvana Alves
França, Thamyris Barbosa de Oliveira
Sousa, Klayton Galante
Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title_full Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title_fullStr Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title_full_unstemmed Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title_short Growth and Development of Children with Microcephaly Associated with Congenital Zika Virus Syndrome in Brazil
title_sort growth and development of children with microcephaly associated with congenital zika virus syndrome in brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164092/
https://www.ncbi.nlm.nih.gov/pubmed/30216976
http://dx.doi.org/10.3390/ijerph15091990
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