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Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems
The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164302/ https://www.ncbi.nlm.nih.gov/pubmed/29966277 http://dx.doi.org/10.3390/jfb9030041 |
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author | Akmal, Jan Sher Salmi, Mika Mäkitie, Antti Björkstrand, Roy Partanen, Jouni |
author_facet | Akmal, Jan Sher Salmi, Mika Mäkitie, Antti Björkstrand, Roy Partanen, Jouni |
author_sort | Akmal, Jan Sher |
collection | PubMed |
description | The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinity of target tissues or the selected medication route in a patient-specific manner as required. The identification and traceability of additively manufactured implants can be administered through radiofrequency identification systems. The focus of this study is to explore how embedded medication and sensors can be added in different additive manufacturing processes. The concept is extended to biomaterials with the help of the literature. As a result of this study, a patient-specific drug delivery device can be custom-designed and additively manufactured in the form of an implant that can identify, trace, and dispense a drug to the vicinity of a selected target tissue as a patient-specific function of time for bodily treatment and restoration. |
format | Online Article Text |
id | pubmed-6164302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61643022018-10-12 Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems Akmal, Jan Sher Salmi, Mika Mäkitie, Antti Björkstrand, Roy Partanen, Jouni J Funct Biomater Article The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinity of target tissues or the selected medication route in a patient-specific manner as required. The identification and traceability of additively manufactured implants can be administered through radiofrequency identification systems. The focus of this study is to explore how embedded medication and sensors can be added in different additive manufacturing processes. The concept is extended to biomaterials with the help of the literature. As a result of this study, a patient-specific drug delivery device can be custom-designed and additively manufactured in the form of an implant that can identify, trace, and dispense a drug to the vicinity of a selected target tissue as a patient-specific function of time for bodily treatment and restoration. MDPI 2018-06-29 /pmc/articles/PMC6164302/ /pubmed/29966277 http://dx.doi.org/10.3390/jfb9030041 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Akmal, Jan Sher Salmi, Mika Mäkitie, Antti Björkstrand, Roy Partanen, Jouni Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title | Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title_full | Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title_fullStr | Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title_full_unstemmed | Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title_short | Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems |
title_sort | implementation of industrial additive manufacturing: intelligent implants and drug delivery systems |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164302/ https://www.ncbi.nlm.nih.gov/pubmed/29966277 http://dx.doi.org/10.3390/jfb9030041 |
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