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In Silico HCT116 Human Colon Cancer Cell-Based Models En Route to the Discovery of Lead-Like Anticancer Drugs

To discover new inhibitors against the human colon carcinoma HCT116 cell line, two quantitative structure–activity relationship (QSAR) studies using molecular and nuclear magnetic resonance (NMR) descriptors were developed through exploration of machine learning techniques and using the value of hal...

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Detalles Bibliográficos
Autores principales:	Cruz, Sara, Gomes, Sofia E., Borralho, Pedro M., Rodrigues, Cecília M. P., Gaudêncio, Susana P., Pereira, Florbela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164384/ https://www.ncbi.nlm.nih.gov/pubmed/30018273 http://dx.doi.org/10.3390/biom8030056

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